2- 5-(cyclic amino)ethyl-10,11-dihydro-5h-dibenzo a, d...

Details 2- 5-(cyclic amino)ethyl-10,11-dihydro-5h-dibenzo a, d... 2- 5-(cyclic amino)ethyl-10,11-dihydro-5h-dibenzo a, d...

C - Chemistry, Metallurgy

07

D

260/303, 260/241

C07D 271/10 (2006.01) C07D 413/10 (2006.01) C07D 453/06 (2006.01)

Patent

CA 1085825

Abstract of the Disclosure This invention encompasses novel 2-[5-(cyclic amino)ethyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-yl]- 5-alkyl-1,3,4-oxadiazoles and congeners. These compounds are useful anti-diarrheal agents and possess little or no analgesic activity. These compounds are prepared by react- ing the appropriate tetrazoles in the presence of a solvent such as pyridine with a suitable anhydride or acid chloride to give the oxadiazoles.

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