Process for producing optically active .alpha.-...

C - Chemistry – Metallurgy – 07 – C

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260/478.1, 260/4

C07C 69/68 (2006.01) B01J 31/24 (2006.01) C07D 307/32 (2006.01)

Patent

CA 1109479

ABSTRACT OF THE DISCLOSURE An optically active .alpha.-hydroxycarboxylic acid ester is produced by asymmetric hydrogenation of an .alpha.-ketocarboxylic acid ester in the presence of a rhodium complex having a phosphine ligand having an optically active substituent group which present is derived from natural sources.

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