Method of forming multilayer immunologically complexed films

Details Method of forming multilayer immunologically complexed films Method of forming multilayer immunologically complexed films

G - Physics

01

N

167/44

G01N 33/48 (2006.01) G01N 33/553 (2006.01)

Patent

CA 1039649

METHOD FOR BINDING ANTIBODIES TO A SURFACE SUCH THAT THEY REMAIN ACTIVE Abstract of the Disclosure An immunologically inert protein of sufficient quantity is added to a solution containing a first immunologically reactive protein (antigen). A substrate is then immersed in the solution and on the surface thereof is formed, by adsorption, a monomolecular layer of the reactive protein molecules separated from each other to distances of several hundred Angstrom by the inert protein molecules. Subsequent immersion of the coated substrate in solutions alternately containing a second immunologically reactive protein (antibody) specific to the first reactive protein, and then again containing the first reactive protein, forms a multi- molecular immunologically complexed film on the substrate.

207062

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