Novel substituted heterocyclic benzamides, process for their...

Details Novel substituted heterocyclic benzamides, process for their... Novel substituted heterocyclic benzamides, process for their...

C - Chemistry, Metallurgy

07

D

260/325.2, 260/3

C07D 403/12 (2006.01) C07C 65/21 (2006.01) C07C 65/28 (2006.01) C07D 207/04 (2006.01) C07D 207/08 (2006.01) C07D 207/09 (2006.01) C07D 207/14 (2006.01)

Patent

CA 1133477

A B S T R A C T The invention relates to novel heterocyclic benz- amides of the general formula: Image wherein R4 is a cycloalkyl, cycloalkenyl, bicycloalkyl or tricycloalkyl; A is a single bond or a saturated or unsatu- rated hydrocarbon chain of 1 to 3 carbon atoms; n is equal to 0. 1, 2 or 3; R5 is a hydrogen atom, an alkyl group of 1 to 3 carbon atoms or an alkenyl or alkynyl group; R1, R2, R3 and R6 are hydrogen or halogen atoms, alky1, alkoxy, amino, acetamino, sulphamoyl, alkylsulphamoyl, dialkylsulphamoyl, alkylsulphony1 or alkylsulphinyl groups or are bonded together to form an azimido group. The compounds of the present invention possess antiemetic properties and act on the central nervous system.

319968

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