Pyrazolopyridine ketones

Details Pyrazolopyridine ketones Pyrazolopyridine ketones

C - Chemistry, Metallurgy

07

D

260/273

C07D 471/04 (2006.01)

Patent

CA 1085849

Abstract New pyrazolo[3,4-b]pyridine-5-ketones having the general formula Image as well as their salts wherein R1 is hydrogen, lower alkyl or phenyl-lower alkylene; R2 and R5 each is hydrogen or lower alkyl; R3 is hydroxy, lower alkoxy or Image wherein R6 is hydrogen or lower alkyl and R7 is hydrogen, lower alkyl, cyclo-lower alkyl, phenyl, phenyl-lower alkylene or di-lower alkylamino-lower alkylene; R4 is pyrrolidinyl, thienyl, furanyl, pyrazolyl, piperidinyl, pyridyl, pyrimi- dinyl, pyridazinyl, piperazinyl, (lower alkyl)piperidinyl, di(lower alkyl)piperidinyl or (hydroxy-lower alkyl)pipera- zinyl; and acid addition salts thereof are useful as anti- inflammatory agents and tranquilizers.

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