Morpholine derivatives

C - Chemistry – Metallurgy – 07 – D

Patent

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260/247.5

C07D 265/30 (2006.01) C07D 265/32 (2006.01) C07D 303/04 (2006.01) C07F 9/6533 (2006.01)

Patent

CA 1067075

ABSTRACT OF THE DISCLOSURE Norpholine derivatives, typically those of the formula:- Image wherein A is an ethylene or vinylene radical and X is a phenyl radical optionally substituted by one or two substituents selected from halogen atoms, alkyl and alkoxy radicals of 1 to 6 carbon atoms and aryloxy radicals of 6 to 10 carbon atoms, the aryloxy radicals themselves being optionally substituted by one or two substituents selected from halogen atoms and alkyl radicals of 1 to 4 carbon atoms, and the pharmaceutically-acceptable acid-addition salts thereof. Processes for making these compounds, pharmaceutical compositions containing them and a method of restoring to normal abnormal mental states in warm-blooded animals are also disclosed.

226313

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