Thiazole derivatives and process for preparing same

Details Thiazole derivatives and process for preparing same Thiazole derivatives and process for preparing same

C - Chemistry, Metallurgy

07

D

195/129, 260/308

C07D 277/24 (2006.01) C07D 277/30 (2006.01)

Patent

CA 1053683

ABSTRACT OF THE DISCLOSURE: The present invention relates to novel thiazole deriva- tives of the general formula I (I) Image wherein R1 and R2 stand for hydrogen atoms or alkyl groups, and R3 stands for an oxo, hydroxyl or acyloxy group. Furthermore, the in- vention relates to processes for preparing these compounds. On investigating the biological properties of the compounds of the general formula I, it has been found that they have prostaglandin- like effects on certain organs. From the aspect of therapeutic application their action is more selective than that of native prostaglandins. They possess the valuable property of inhibiting the activity of enzymes inducing the decomposition of prostaglan- dins in the organism and thus they promote the rise of the endoge- nous level of prostaglandins.

226932

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