Process for the preparation of novel derivatives of...

B - Operations – Transporting – 01 – J

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260/595.5

B01J 23/44 (2006.01) A61K 9/20 (2006.01) A61K 31/04 (2006.01) A61K 31/135 (2006.01)

Patent

CA 1115294

PRECIS DE LA DIVULGATION : L'invention a pour objet un procédé de préparation de nouveaux dérivés de la 5H-benzocyclohepten-7-amine et de leurs sels, de formule I : Image (I') dans laquelle R1 représente un hydrogène ou un méthyle, R2 et R3 présentent un hydrogène, un fluor, un chlore ou un brome, un radi- cal nitro, amino, trifluorométhyle ou méthoxy et X représente un hydrogène ou un halogène. Les dérivés selon l'invention sont doués de propriétés inhibitrices sur la captation de la sérotonine in vitro et in vivo et certains de propriétés anorexigènes.

315360

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