Process for preparing anthracycline glycosides

Details Process for preparing anthracycline glycosides Process for preparing anthracycline glycosides

C - Chemistry, Metallurgy

07

H

260/208.2

C07H 15/24 (2006.01) C07D 309/14 (2006.01) C07H 13/04 (2006.01) C07H 15/252 (2006.01)

Patent

CA 1060002

ABSTRACT OF THE DISCLOSURE The novel compounds, 4'-deoxy-daunomycin and 4'- deoxy-adriamycin, as well as derivatives thereof are useful as antitumor antibiotics. These compounds are prepared by con- densing the corresponding aglycone with a novel trifluoroacetyl protected reactive halo sugar which is 2,3,4,6-tetradeoxy-3- trifluoroacetamido-L-threo-hexopyranosyl chloride.

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