Crystalline forms of prazos in hydrochloride

Details Crystalline forms of prazos in hydrochloride Crystalline forms of prazos in hydrochloride

C - Chemistry, Metallurgy

07

D

260/253

C07D 407/14 (2006.01) A61K 31/505 (2006.01) C07D 405/14 (2006.01)

Patent

CA 1068269

ABSTRACT OF THE DISCLOSURE The invention relates to novel and valuable crystal- line forms of the hypotensive agent prazosin hydrochloride. The anhydrous .alpha.-from is preferred because it is relatively non- hygroscopic and hence possesses important advantages in handling and formulation. The polyhydrate form of prazosin hydrochloride is preferred because of its low, uniform rate of dissolution.

272080

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