C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
260/488, 260/526
C07C 59/76 (2006.01) C07C 51/373 (2006.01) C07C 69/716 (2006.01)
Patent
CA 1152527
Abstract of the disclosure: Process for the manufacture of 5-oxoalkanoic acids, their esters or nitrils, by reaction of a ketone containing at least one .alpha.-hydrogen atom, at elevated temperature, with an .alpha.,.beta.-unsaturated acid, its ester or nitril, in the liquid phase, in the presence of at least one compound selected from the group consisting of: primary amines, primary aminoalcohols, primary aminocarboxylic acids, Schiff's bases of primary amines and the ketone used, and, if .alpha.,.beta.-unsaturated carboxylic acid eaters are reacted, the .beta.,aminopropionates formed from the latter esters and primary amines, which comprises conducting the reaction under a pressure above the vapor pressure of the reaction mixture and below 500 bars.
342369
Muller Werner H.
Popp Knut I.
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Hoechst Aktiengesellschaft
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