Substituted 2-phenylamino-imidazolines-(2), their acid...

C - Chemistry – Metallurgy – 07 – D

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260/314.7

C07D 233/50 (2006.01)

Patent

CA 1121824

ABSTRACT Substituted 2-phenylamino-2-imidazolines of general formula Image (wherein R1 and R2 independently represent hydrogen,ohlorine or methyl, with the proviso that at least one of R1 and R2 is other than hydrogen, and R represents a group of form- ula -(CH2)2-C(CH3)=CH2, -(CH2)2-CH=CH2, -O-CH2-CH=CH2, -O-(CH2)2-CH=CH2, -O-CH2-C(CH3)=CH2, -O-CH2-CH=CH-CH3, Image , -CH2-C6H5, -CH2-CH=CH-C6H5, Image , Image Image or Image and acid addition salts thereof. The compounds exhibit analgesic and bradycardiac activities. Processes for the preparation of the compounds, and their use in pharmaceuti- cal compositions are described and exemplified.

332040

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