Process for 11a dehalogenation of 11a halo tetracyclines

C - Chemistry – Metallurgy – 07 – C

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260/208.6

C07C 49/82 (2006.01) A61K 31/65 (2006.01)

Patent

CA 1110618

ABSTRACT OF THE DISCLOSURE The 11a-dehalogenation of 11a-halo-6-methylenetetra cyclines by treating them with a secondary phosphine or a tertiary phosphite.

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