Producing 7-alkoxycarbonyl-6,8-dimethyl-4-...

Details Producing 7-alkoxycarbonyl-6,8-dimethyl-4-... Producing 7-alkoxycarbonyl-6,8-dimethyl-4-...

C - Chemistry, Metallurgy

07

D

260/361.9

C07D 307/88 (2006.01)

Patent

CA 1151659

ABSTRACT A process for producing 6-alkoxycarbonyl-5,7-dimethyl-.DELTA.3,.alpha.- substituted methylenephthalide. This compound can be prepared by reacting a 3,5-dimethyl-4-alkoxy carbonylphthalic anhydride with a substituted methylenetriphenylphosphorane. The product of this reaction is a useful intermediate in the preparation of 7-alkoxycarbonyl-6,8-dimethyl-4-hydroxymethyl- 1-phthalazone, a blood platelet anti-coagulant and phosphodiesterase inhibitor.

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