C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/326
C07D 207/337 (2006.01) C07D 207/34 (2006.01) C07D 207/416 (2006.01) C07D 261/18 (2006.01)
Patent
CA 1133917
4-12389/CGC 892/+ Canada Alphacarbamoyl-pyrrolpropionitriles, process for their manufacture, pharmaceutical preparations containing these compounds and their therapeutic application. Abstract of the disclosure The invention concerns the manufacture of compounds of the formula Image (I) wherein P1 is 2- or 3-pyrrolyl substituted in 1-position by lower alkyl or Ph-lower alkyl and being unsubstituted in the remaining 3 positions, or substituted therein by lower alkyl and/or one carboxy or lower carbalkoxy; R is hydrogen or lower alkyl, and Ph is phenyl, unsubstituted or substituted by one to throe identical or different members selected from lower alkyl, lower alkoxy, lower alkylthio, hydroxy, halogeno, trifluoromethyl, nitro, amino or lower alkanoyl- amino; of these compounds in their enol form, a lower alkyl enol ether or a lower alkanoyl enol-ester, or a salt thereof derived from a base. The compounds exhibit antiinflammatory and antiarthritic activity. They are prepared by condensing compounds of the formula Image wherein X is lower alkoxy, lower alkanoyloxy or halogeno.
353624
Fetherstonhaugh & Co.
Novartis Ag
LandOfFree
Alphacarbamoyl-pyrrolpropionitriles, process for their... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Alphacarbamoyl-pyrrolpropionitriles, process for their..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Alphacarbamoyl-pyrrolpropionitriles, process for their... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-866977