C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
260/526, 530/1.0
C07K 1/12 (2006.01) C07K 1/06 (2006.01) C07K 5/06 (2006.01) C07K 5/083 (2006.01) C07K 5/103 (2006.01) C07K 14/655 (2006.01)
Patent
CA 1074300
ABSTRACT OF THE DISCLOSURE A novel method for removal of protective group(s) from an amino acid or peptide having thiol group(s) protected with p-methoxybenzyl, 1-adamantyl or t-butyl group by treating the protected amino acid or peptide with mercuric salt of acetic acid or halogenoacetic acid, the removal being effected selectively and very smoothly in a good yield under extremely mild condition without giving any undesirable influence upon other functional or protective group(s).
279924
Fujino Masahiko
Kitada Chieko
Nishimura Osamu
Na
Takeda Chemical Industries Ltd.
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