Steroid 5.alpha.-reductase inhibitors

Details Steroid 5.alpha.-reductase inhibitors Steroid 5.alpha.-reductase inhibitors

C - Chemistry, Metallurgy

07

J

260/21, 260/28.1

C07J 1/00 (2006.01) C07J 3/00 (2006.01) C07J 7/00 (2006.01) C07J 9/00 (2006.01) C07J 17/00 (2006.01) C07J 21/00 (2006.01) C07J 31/00 (2006.01) C07J 41/00 (2006.01) C07J 51/00 (2006.01)

Patent

CA 1154008

ABSTRACT Compound of the following general formula are testosterone 5c-reductase inhibitors rendering the com- pounds useful in the treatment of acne and oily skin and benign prostatic hypertrophy: Image wherein R is: -O, -OH, -OCO-alkylC: 5, -COOH, -CH2CH, -COOalkylC1-?, -COCH3, Image , Image , Image and the 20? isomers of Image , Image , Image or Image .

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