Oxazolidine compounds

Details Oxazolidine compounds Oxazolidine compounds

C - Chemistry, Metallurgy

07

D

260/298.2

C07D 498/04 (2006.01)

Patent

CA 1087194

OXAZOLIDINE COMPOUNDS ABSTRACT Compounds represented by the following formula prepared from 6-aminopenicillanic acid are key intermediates in a stereo-specific synthesis of 1-oxadethiacephalosporins, highly active antibiotics: Image , Image , Image , or Image [wherein COA and COB each is carboxy or protected carboxy; COX is carboxy, protected carboxy, or a group of the formula -COCQ=N2 or -COCHQ-Z (in which Q is hydrogen, lower alkyl or aryl; and z is hydrogen or a nucleophilic group); Hal is halogen; R is lower alkyl or aralkyl; and Y is hydrogen or acyl].

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