Process for the manufacture of new 1-amino-2-hydroxy-...

Details Process for the manufacture of new 1-amino-2-hydroxy-... Process for the manufacture of new 1-amino-2-hydroxy-...

C - Chemistry, Metallurgy

07

D

260/268, 260/295

C07D 213/60 (2006.01) C07D 213/64 (2006.01) C07D 213/69 (2006.01) C07D 213/85 (2006.01) C07D 237/10 (2006.01) C07D 241/18 (2006.01) C07D 263/06 (2006.01) C07D 405/12 (2006.01)

Patent

CA 1105021

Abstract of the Disclosure l-Amino-2-hydroxy-3-heterooyclyloxy-propanes of the formula Image wherein Y represents the group - CH = or the group - N = , R1 represents hydrogen, hydroxyl, lower alkyl or lower alkoxy, R2 represents hydroxyl, lower alkoxy or, together with R1, o-lower-alkylidenedioxy or o-lower-alkylenedioxy, and R3 represnts lower alkyl, lower alkoxy, halogen or cyano, with the radicals R1, R2 and R3 each being bound to any one of the possible aromatic carbon atoms, optical antipodes and salts thereof having cardioselective beta-receptor-blocking and also alpha-receptor-blocking together with hypotensive properties which render such compounds suitable for the treatment of angina pectoris, hyypertonia or disturbances of the heart rhythm. - 1 -

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