Non-adhesive ionene quaternary polymer compositions and process

Details Non-adhesive ionene quaternary polymer compositions and process Non-adhesive ionene quaternary polymer compositions and process

A - Human Necessities

61

K

167/206

A61K 31/74 (2006.01) A61K 9/14 (2006.01) A61K 31/785 (2006.01)

Patent

CA 1109395

15970 Abstract of the Disclosure The invention disclosed herein relates to a novel non-adhesive,free-flowing, pharmacologically acceptable composition comprising ionene quaternary polymers effec- tive as bile acid sequestrants, such as poly-[{methyl-(3- trimethylammoniopropyl)iminio}trimethylene dichloride], adsorbed on a pulverulent, solid aggregate of large sur- face to mass ratio, such as fumed silica. It also relates to the novel process for preparing such adsorbate composi- tions which comprises forming a substantially, uniform suspension of the finely-divided solid aggregate in an aqueous solution of poly-[{methyl-(3-trimethylammoniopropyl)- iminio}trimethylene dichloride], evaporatively removing the water from the suspension, and drying the adsorbate thus produced.

296622

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