Process for the production of factor xa preparation

G - Physics – 01 – N

Patent

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150/11, 167/103.

G01N 33/86 (2006.01)

Patent

CA 1150607

ABSTRACT OF THE DISCLOSURE A process is provided for the production of a Factor Xa preparation, comprising treating plasma with a prothrombin activator, removing suspended solids, mixing the thus obtained plasma liquid with a protein adsorbent to form a precipitate, eluting the precipitate with a protein elution agent and mixing the thus obtained eluate with-a Factor X activator, the Factor Xa pre- paration is employed in the determination of prothrombin for example, in the continuous monitoring of anticoagulation therapy.

387534

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