Process for the preparation of 3-amino (1h-3h)...

Details Process for the preparation of 3-amino (1h-3h)... Process for the preparation of 3-amino (1h-3h)...

C - Chemistry, Metallurgy

07

D

260/254, 260/245

C07D 239/96 (2006.01) C07D 403/04 (2006.01)

Patent

CA 1130285

ABSTRACT OF THE DISCLOSURE: This invention relates to a process for the preparation of compounds having the formula: Image in which R1 and R2 are independently hydrogen, a C1-4 alkyl group, a C2-4 aliphatic acyl group or a benzenoid aromatic acyl group, provided R1 and R2 are not simultaneously hydrogen, or, together with the nitrogen atom to which they are attached, R1 and R2 form a 5- or 6- membered ring which may carry an oxygen atom R3 is a C1-4 alkyl group; and R4 and R5 represent independently a hydrogen or halogen atom, a C1-4 alkyl group or a C1-4 alkoxy groups and the acid addition salts of the above compounds. These new compounds have an anxiolytic and diuretic action, together with a spasmolytic action of non-.alpha.-adrenalytic nature on the unstriated muscle fibers.

347528

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