C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/266.7
C07D 405/06 (2006.01) C07D 295/18 (2006.01) C07D 307/68 (2006.01)
Patent
CA 1102332
ABSTRACT OF THE DISCLOSURE Anovel benzonitrile, namely 3,4-dimethoxy-6-[4-(2-furoyl)-1-piper- azinylthiocarbamide] benzonitrile is provided herein. It may be prepared by carrying out one of the following reaction, namely (a) reacting 3,4-dimethoxy- 6-aminobenzonitrile having the formula Image (IV) with thiophosgene, to form 3,4-dimethoxy-6-isothiocyanatobenzonitrile having the formula Image (V) and then reacting compound (V) with 1-(2-furoyl)piperazine having the formula Image (VI) or (b) reacting 1-(2-furoyl)piperazine (Formula VI) with thiophosgene to form 4-(2-furoyl)-piperazinylthiocarbonyl chloride having the formula Image (VII ) and then reacting compound (VII) with 3,4-dimethoxy-6-amlnobenzonitrile (Formula (IV). The product is an intermediate in the production of the anthibypertensive drug prazosine by a process in which the formation of the quinazoline ring of prazosine occurs within the molecule.
293066
Honkanen Erkki J.
Pippuri Aino K.
Marcus & Associates
Orion-Yhtyma Oy
LandOfFree
Intermediate product for the production of 6,7-... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Intermediate product for the production of 6,7-..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Intermediate product for the production of 6,7-... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-980583