Process for preparing aniline compounds

B - Operations – Transporting – 01 – J

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260/601

B01J 27/00 (2006.01)

Patent

CA 1113963

Abstract An improved process is provided for the production of thioalkyl aniline compounds, which are known and useful as intermediates for producing anthelmintic, antibacterial and fungicidal benzimidazole compounds. According to the process a thiocyano aniline compound, an alcohol and an alkali metal cyanide are reacted, with the additional presence of an alkyl halide, and also with a dipolar aprotic solvent, or in the presence of an immiscible solvent and a phase transfer catalyst. A further improvement consists of providing said phase transfer catalyst as a polymer-bound catalyst.

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