C - Chemistry – Metallurgy – 07 – D

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C07D 487/04 (2006.01) A61K 31/5025 (2006.01) A61P 3/00 (2006.01) A61P 25/00 (2006.01) C07D 495/04 (2006.01)

Patent

CA 2668196

The invention relates to compounds having the formula (I), wherein R1 represents: a substituted or non-substituted (C1-C12)alkyl; a non aromatic (C3-C12) carbocylic substituted or non substituted radical; a substituted or non substituted phenyl; a substituted or non substituted benzyl; a substituted or non substituted phenethyl; a benzhydryl; a benzhydrylmethyl; a heterocyclic aromatic radical; R2 represents a non substituted or substituted phenyl; R3 represents a substituted or non substituted phenly; R4 represents a hydrogen atom, a (C1-C-4)alkyl, a (C1-C4)alcoxy, a hydroxy; AIk represents a substituted or non substituted (C1-C4)alkyl. The invention also relates to the method for preparing same and to the use thereof in therapeutics as central and/or peripheral cannabinoid CB1 receptor ligands.

La présente invention a pour objet des composés répondant à la formule (I) dans laquelle : - R1 représente : un (C1-C12)alkyle non substitué ou substitué; un radical carbocyclique non aromatique en (C3-C12) non substitué ou substitué; un phényle non substitué ou substitué; un benzyle non substitué ou substitué; un phénéthyle non substitué ou substitué; un benzhydryle; un benzhydrylméthyle; un radical hétérocyclique aromatique; - R2 représente un phényle non substitué ou substitué; - R3 représente un phényle non substitué ou substitué; - R4 représente un atome d'hydrogène, un (C1 -C4)alkyle, un (C1-C4)alcoxy, un hydroxy; - AIk représente un (C1 -C4)alkyle non substitué ou substitué. Procédé de préparation et application en thérapeutique, comme ligands des récepteurs CB1 des cannabinoïdes localisés au niveau central et/ou périphérique.

LandOfFree

Say what you really think

Search LandOfFree.com for Canadian inventors and patents. Rate them and share your experience with other people.

Rating

does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with , we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFCA-PAI-O-1438884

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.