Details

A - Human Necessities

61

K

A61K 31/42 (2006.01) A61K 9/70 (2006.01)

Patent

CA 2370581

The invention relates to novel pharmaceutical compositions comprising 2-isoxazole-8-aminotetralin derivatives. The invention more specifically relates to compositions in the form of a patch comprising a therapeutically efficacious amount of a derivative of 2-isoxazole-8-aminotetraline, especially 1,2,3,4-tetrahydro-8-(5-isoxazolyl)-N-N-diisopropyl-2-naphtalenamine. The invention also relates to a 2-isoxazole-8-aminotetralin derivative, especially 1,2,3,4-tetrahydro-8-(5-isoxazolyl)-N,N-diisopropyl-2-naphtalenamine, which is used to produce a medicament which can be administered transdermally to treat irritable bowel syndrome.

L'invention a pour objet des nouvelles compositions pharmaceutiques comprenant des dérivés de 2-isoxazoles-8-aminotétralines. Elle concerne notamment des compositions sous forme de patch, lequel comprend un dérivé de 2-isoxazole-8-aminotétraline, et en particulier de la 1,2,3,4-tétrahydro-8-(5-isoxazolyl)-N,N-diisopropyl-2-naphtalènamine en quantité thérapeutiquement efficace. Elle concerne aussi l'utilisation d'un dérivé de 2-isoxazole-8-aminotétraline, et en particulier de la 1,2,3,4-tétrahydro-8-(5-isoxazolyl)-N,N-diisopropyl-2-naphtalènamine, pour fabriquer un médicament permettant une administration transdermale, notamment dans le traitement du syndrome du colon irritable.

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