Details

A - Human Necessities

61

K

A61K 9/06 (2006.01) A61K 9/10 (2006.01) A61K 31/728 (2006.01) A61K 47/10 (2006.01) A61P 19/00 (2006.01)

Patent

CA 2691600

The invention relates to a sterile injectable aqueous formulation in the form of a gel made up of hyaluronic acid (or one of the salts thereof) with or without other natural polysaccharide(s) and one or more polyols. Said formulation is of intra-articular application in the treatment of joint degeneration,in some cases having a rheology similar to that of synovial liquid and always with an elevated resistance to degradation due to a synergistic action between the hyaluronic acid and the polyols.

L'invention concerne une formulation aqueuse injectable stérile sous forme de gel composée d'acide hyaluronique (ou l'un de ses sels) avec ou sans autre(s) polysaccharide(s) d'origine naturelle et d'un ou plusieurs polyol(s). Cette formulation est utilisée en intra-articulaire dans le traitement des dégénérescences articulaires. Elle présente dans certains cas une rhéologie proche de celle du liquide synovial et toujours une résistance accrue à la dégradation grâce à un effet synergique entre l'acide hyaluronique et le ou les polyols.

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