0rally active derivatives of 1,3,5(10)-estratriene

Details 0rally active derivatives of 1,3,5(10)-estratriene 0rally active derivatives of 1,3,5(10)-estratriene

C - Chemistry, Metallurgy

07

J

C07J 41/00 (2006.01) A61K 31/56 (2006.01)

Patent

CA 2171740

17.beta.-nitrate and 11.beta.,17.beta.-dinitrate esters of estradiol which exibit elevated estrogenic and postcoital contraceptive activities are disclosed. A process for their manufacture and their use in pharmaceuticals is also disclosed.

L'invention concerne décrit des dinitrate-17 beta -nitrate et 11 beta -,17 beta -ester d'estradiol, qui présentent une activité oestrogénique et contraceptive postcoïtale élevée. Un procédé pour leur fabrication et leur utilisation dans des produits pharmaceutiques est également décrit.

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