1,1,1-trifluoro-4-phenyl-4-methyl-2-(1h-pyrrolo(2,3-c)...

Details 1,1,1-trifluoro-4-phenyl-4-methyl-2-(1h-pyrrolo(2,3-c)... 1,1,1-trifluoro-4-phenyl-4-methyl-2-(1h-pyrrolo(2,3-c)...

C - Chemistry, Metallurgy

07

D

C07D 471/04 (2006.01) A61K 31/33 (2006.01) A61K 31/395 (2006.01) A61K 31/437 (2006.01) A61K 31/475 (2006.01) C07D 209/32 (2006.01) C07D 215/12 (2006.01) C07D 231/56 (2006.01) C07D 307/79 (2006.01) C07D 401/10 (2006.01) C07D 401/14 (2006.01) C07D 403/10 (2006.01) C07D 405/10 (2006.01) C07D 405/14 (2006.01) C07D 487/04 (2006.01) C07D 491/04 (2006.01) C07D 495/04 (2006.01) G01N 33/50 (2006.01)

Patent

CA 2539909

Compounds of Formula (IA), IB), IC), and (ID) wherein R1, R2, R3, R4, R5, and R6 are as respectively defined herein for Formula (IA), (IB), (IC), and (ID), or a tautomer, prodrug, solvate, or salt thereof; pharmaceutical compositions containing such compounds, and methods of modulating the glucocorticoid receptor function and methods of treating disease-states or conditions mediated by the glucocorticoid receptor function or characterized by inflammatory, allergic, or proliferative processes in a patient using these compounds.

La présente invention a trait à des composés de formules (IA), IB), IC), et (ID) dans lesquelles R?1¿, R?2¿, R?3¿, R?4¿, R?5¿, et R?6¿ sont respectivement tels que définis pour les formules (IA), (IB), (IC), et (ID), ou un tautomère, prodrogue, solvate, ou sel de ceux-ci ; à des compositions pharmaceutiques contenant de tels composés, et à des procédés de modulation de la fonction du récepteur des glucocorticoïdes et à des procédés de traitement de maladies ou de conditions liées à la fonction du récepteur des glucocorticoïdes ou caractérisées par des processus inflammatoires, allergiques, ou proliférants chez un patient utilisant de tels composés.

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