C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 401/04 (2006.01) A61K 31/454 (2006.01) A61P 5/50 (2006.01) C07D 401/14 (2006.01) C07D 405/14 (2006.01) C07D 471/04 (2006.01)
Patent
CA 2682287
This invention relates to compounds of the formula (I) wherein A, R1 to R3 are as defined in the specification and G is benzoimidazole, quinoxaline, benzotriazole, dihydro-imidazo[4,5-c]pyridinone and dihydro-isoindolone group as defined in the specification, and pharmaceutically acceptable salts thereof. The invention further relates to pharmaceutical compositions containing such compounds, to a process for their preparation and to their use for the treatment and/or prevention of diseases which are associated with the modulation of SST receptors subtype 5.
La présente invention concerne des composés de formule (I), dans laquelle: A, R1 à R3 sont tels que définis dans la description et G est un groupe benzoimidazole, quinoxaline, benzotriazole, dihydro-imidazo[4,5-c]pyridinone et dihydro-isoindolone tel que défini dans la description, ainsi des leurs sels pharmaceutiquement acceptables. L'invention concerne également des compositions pharmaceutiques contenant de tels composés, leur procédé de préparation et leur utilisation pour le traitement et/ou la prévention de maladies associées à la modulation des récepteurs SST de sous-type 5.
Bleicher Konrad
Christ Andreas D.
Martin Rainer E.
Mohr Peter
F. Hoffmann-La Roche Ag
Gowling Lafleur Henderson Llp
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