1,1-diaminoalkane derived sweeteners

C - Chemistry – Metallurgy – 07 – C

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C07C 61/15 (2006.01) A23L 1/227 (2006.01) A61K 8/44 (2006.01) A61Q 11/00 (2006.01) C07C 13/11 (2006.01) C07C 29/04 (2006.01) C07C 29/40 (2006.01) C07C 45/68 (2006.01) C07C 49/395 (2006.01) C07C 53/128 (2006.01) C07C 53/132 (2006.01) C07C 53/42 (2006.01) C07C 53/44 (2006.01) C07C 61/06 (2006.01) C07C 61/08 (2006.01) C07D 331/04 (2006.01)

Patent

CA 1221683

82-226 GEM-DIAMINOALKANE DERIVED SWEETENERS ABSTRACT OF THE DISCLOSURE Compounds of the formula: Image (I) wherein n is 0 or 1, R is lower alkyl (substituted or unsubstituted), R' is H or lower alkyl, and R" is a branched alkyl, alkyl-cycloalkyl, cycloalkyl, polycycloalkyl (poly = 2 or more, fused or non-fused), phenyl or alkyl-substituted phenyl, and physiologically acceptable cationic and acid addition salts thereof, which compounds are potent sweeteners. These derivatives of gem-diaminoalkanes are many times sweeter than sugar and are free from undesirable flavor qualities. Furthermore, they possess an unanticipated high degree of solubility compared with known synthetic sweeteners. In addition, the compounds possess high stability so that they can be used is all types or beverages and in conventional food processing. Sweetening composi- tions and sweetened edible compositions of these compounds are also provided.

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