C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/303, 260/278
C07D 413/10 (2006.01) C07D 211/32 (2006.01) C07D 221/22 (2006.01) C07D 271/10 (2006.01) C07D 453/06 (2006.01) C07D 487/08 (2006.01)
Patent
CA 1053672
ABSTRACT OF THE DISCLOSURE The present invention is concerned with 1,1-diaryl-1-oxadiazol-alkylamines. These compounds are prepared by reacting the tetrazoles of the present invention in the presence of a solvent such as pyridine with a suitable anhydride or acid chloride to give the oxadiazoles. The compounds of the present invention possess potent anti-diarrheal utility as evidenced by their ability to inhibit gastro-intestinal motility. These subject compounds also possess a very low degree of analgesia.
223487
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