1, 2, 3, 3a, 8, 8a-hexahydro-2, 7a-diada-cyclopenta [a]...

Details 1, 2, 3, 3a, 8, 8a-hexahydro-2, 7a-diada-cyclopenta [a]... 1, 2, 3, 3a, 8, 8a-hexahydro-2, 7a-diada-cyclopenta [a]...

C - Chemistry, Metallurgy

07

D

C07D 471/14 (2006.01) A61P 25/34 (2006.01)

Patent

CA 2591330

The present invention relates to novel fused bicyclicpyrrolidine pyridone compounds of the formula (I) wherein R, RP and n are as defined herein, their pharmaceutically acceptable salts, pharmaceutical compositions and their use in treating addictive disorders such as the use of tobacco or other nicotine containing products and in the treatment of neurological and mental disorders related to a decrease in cholinergic function.

L'invention concerne de nouveaux composés bicyclicpyrrolidine pyridone fusionnés de formule I: (I), dans laquelle R, Rp et n sont tels que définis dans la description, leurs sels pharmaceutiquement acceptables, des compositions pharmaceutiques, ainsi que leur utilisation dans le traitement de troubles de dépendance, tels que l'usage du tabac et autres produits contenant de la nicotine, et dans le traitement de troubles neurologiques et mentaux liés à une fonction cholinergique diminuée.

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