1,2,3,4-tetrahydro-naphthalenes

Details 1,2,3,4-tetrahydro-naphthalenes 1,2,3,4-tetrahydro-naphthalenes

C - Chemistry, Metallurgy

07

D

260/351, 260/393

C07D 317/54 (2006.01) C07D 317/58 (2006.01)

Patent

CA 1105475

Abstract of the Disclosure: The invension provides compounds of formula I, Image I wherein R1 is, for example, hydrogen or alkanoyl of 1 to 20 carbon atoms; R2 is, for example, hydrogen, hydroxy, alkanoyl of 1 to 20 car- bon atoms, CF3SO2NH or CC13SO2NH; R3 is hydrogen or, when R2 is chlorine, R3 may also be chlorine; R4 is, for example, hydrogen, alkyl of 1 to 4 carbon atoms or cycloalkyl of 3 to 8 carbon atoms; and R6 is, for example, hydrogen, alkyl of 1 to 4 carbon atoms or, together with R5, a -(CH2)4-, -(CH2)5 or (CH2)6-group, which compounds possess pharmacological activity, for example in she treatment of cardiac diseases and Parkin- son's disease.

292457

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