1,2,3,4-tetrahydrocyclopent[b]indoles,...

Details 1,2,3,4-tetrahydrocyclopent[b]indoles,... 1,2,3,4-tetrahydrocyclopent[b]indoles,...

C - Chemistry, Metallurgy

07

D

C07D 209/94 (2006.01) A61K 31/40 (2006.01) A61K 31/435 (2006.01) A61K 31/535 (2006.01) C07D 209/80 (2006.01) C07D 209/88 (2006.01) C07D 401/02 (2006.01) C07D 403/00 (2006.01) C07D 413/02 (2006.01)

Patent

CA 2059610

There are disclosed various compounds of the formula below, (see formula I) where n, K and R1 through R4 are as defined in the specification, which are useful for alleviating various memory dysfunctions characterized by a cholinergic deficit such as Alzheimer's disease. Compounds of this invention also inhibit monoamine oxidase and/or act at central .alpha.2-adrenergic receptors, and hence are useful as antidepressants. The invention relates also to intermediates and a process for the preparation of the above compounds.

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