C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 241/08 (2006.01) A61K 31/496 (2006.01) A61P 29/00 (2006.01) C07D 243/08 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01) C07D 405/12 (2006.01) C07D 405/14 (2006.01) C07D 409/12 (2006.01)
Patent
CA 2573730
Selected compounds are effective for treatment of pain and diseases, such as inflammation mediated diseases. The invention encompasses novel compounds of formula (I) and pharmaceutically acceptable derivatives thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving pain, inflammation, and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.
Il est décrit des composés qui sont efficaces pour le traitement de la douleur et de maladies, telles que les maladies à médiation inflammatoire. L'invention concerne de nouveaux composés de formule (I) et des dérivés pharmaceutiquement acceptables de ceux-ci, des compositions pharmaceutiques et des procédés pour la prophylaxie et le traitement de maladies et d'autres pathologies ou troubles mettant en AEuvre une douleur, une inflammation, et similaire. La présente invention concerne en outre des procédés pour préparer de tels composés ainsi que des intermédiaires utiles dans de tels procédés.
Askew Benny C. Jr.
Aya Toshihiro
Biswas Kaustav
Cai Guolin
Chen Jian Jeffrey
Amgen Inc.
Gowling Lafleur Henderson Llp
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