1,2,3,5-tetrahydroimidazothienopyrimidin-2-ones

Details 1,2,3,5-tetrahydroimidazothienopyrimidin-2-ones 1,2,3,5-tetrahydroimidazothienopyrimidin-2-ones

C - Chemistry, Metallurgy

07

D

260/242.01

C07D 495/14 (2006.01) C07D 495/04 (2006.01)

Patent

CA 1116597

D-1-21977C/79 ABSTRACT OF THE DISCLOSURE A 1,2,3,5-tetrahydroimidazothienopyrimidin-2-one represented by the formula: Image wherein one of Z1, Z2 and Z3 is a sulfur atom and the remaining two of Z1, Z2 and Z3 represent CH, R1 and R2 each represents a hydrogen atom, an alkyl group having 1 to 5 carbon atoms, a phenyl group, a chlorine atom or, when taken together R1 and R2 represent an alkylene chain of 3 to 5 carbon atoms, and R3 represents a hydrogen atom or an alkyl group having 1 to 5 carbon atoms, and a pharmaceutically acceptable acid addition salt thereof, which exhibit an excellent blood platelet anti- aggregatory activity and are useful as anti-thrombotic agents.

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