1,2,3,6-tetrahydroazepino[4,5-b]indole-5-carboxylate nuclear...

Details 1,2,3,6-tetrahydroazepino[4,5-b]indole-5-carboxylate nuclear... 1,2,3,6-tetrahydroazepino[4,5-b]indole-5-carboxylate nuclear...

C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01) A61K 31/55 (2006.01) A61P 31/04 (2006.01)

Patent

CA 2736880

Provided are certain 1,2,3,6- tetrahydroazepino[4,5-b]indole-5-carboxylate compounds which are useful for modulating the activity of nuclear receptors, such as farnesoid X receptors, and/or for the treatment, prevention, or amelioration diseases or disorders related to the activity of these receptors.

L'invention porte sur certains composés 1,2,3,6-tétrahydroazépino[4,5-b]indole-5-carboxylates qui sont utiles pour moduler l'activité de récepteurs nucléaires, tels que des récepteurs de farnésoïde X et/ou pour le traitement, la prévention ou l'amélioration de maladies ou d'états pathologiques liés à l'activité de ces récepteurs.

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