1,2,3-triazole amide derivatives as inhibitors of cytokie...

Details 1,2,3-triazole amide derivatives as inhibitors of cytokie... 1,2,3-triazole amide derivatives as inhibitors of cytokie...

C - Chemistry, Metallurgy

07

D

C07D 249/06 (2006.01) A61K 31/4192 (2006.01) A61P 29/00 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01) C07D 405/12 (2006.01) C07D 413/12 (2006.01)

Patent

CA 2547410

Disclosed are compounds of formula (I), where Ar1, X, R3, R4, R5 and R6 are defined herein. The compounds of the invention inhibit production of cytokines and are thus useful for treating cytokine mediated diseases. Also disclosed are processes for preparing these compounds and pharmaceutical compositions comprising these compounds.

L'invention concerne des composés de formule (I), dans laquelle Ar¿1?, X, R¿3?, R¿4?, R¿5? et R¿6? sont tels que définis dans le descriptif. Les composés de cette invention inhibent la production de cytokines et servent au traitement de maladies induites par les cytokines. L'invention concerne également des procédés de préparation des composés de cette invention et des compositions pharmaceutiques comprenant lesdits composés.

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