C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 271/06 (2006.01) A61K 31/382 (2006.01) A61K 31/397 (2006.01) A61K 31/4025 (2006.01) A61K 31/4245 (2006.01) A61K 31/445 (2006.01) A61K 31/541 (2006.01) C07D 413/06 (2006.01) C07D 417/06 (2006.01)
Patent
CA 2564264
The present invention is directed to novel 1,2,4-oxadiazole derivatives which are inhibitors of the dipeptidyl peptidase-IV enzyme ("DP-IV inhibitors") and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularly type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase- IV enzyme is involved.
La présente invention concerne de nouveaux dérivés de 1,2,4-oxadiazole qui constituent des inhibiteurs de l'enzyme de la dipeptidylepeptidase-IV ("inhibiteurs DP-IV ") et qui sont utilisés dans le traitement ou la prévention de maladies, dans lesquelles est impliquée l'enzyme de la dipeptidylepeptidase-IV, telles que des diabètes et, notamment, des diabètes de type 2. Cette invention a également pour objet des compositions pharmaceutiques contenant ces composés et l'utilisation desdits composés et compositions dans la prévention ou le traitement de telles maladies, dans lesquelles est impliquée l'enzyme de la dipeptidylepeptidase-IV.
Edmondson Scott D.
Mastracchio Anthony
Wei Lan
Xu Jinyou
Gowling Lafleur Henderson Llp
Merck & Co. Inc.
LandOfFree
1,2,4-oxadiazole derivatives as dipeptidyl peptidase-iv... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with 1,2,4-oxadiazole derivatives as dipeptidyl peptidase-iv..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 1,2,4-oxadiazole derivatives as dipeptidyl peptidase-iv... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1614621