C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/248.6
C07D 253/06 (2006.01) C07D 253/075 (2006.01) C07D 487/04 (2006.01)
Patent
CA 1103670
Abstract Production of Heterocyclic Compounds Compounds of the formula (I) Image (I) (in which X represents HS- or a group R1R2N- wherein R1 and R2 which may be the same or different represent hydrogen or a straight or branched chain alkyl group containing from 1 to 4 carbon atoms or a benzyl group and R3 represents a C3-7 alkyl group or a C3-7 cycloalkyl group) are prepared by reacting an .alpha.-ketoester of the formula (II) Image (II) (in which Alk represents an alkyl group) or a precursor thereof with a compound of the formula (III) Image (III) The precursor of the compound of formula (II) may be a mixture of isomeric enol esters Image Image (VI) (VII) The compounds of formula (I) may be converted into compounds of formula VIII. (VIII) Image in which R1 and R2 which may be the same or different re- present hydrogen or a straight or branched chain alkyl group containing from 1 to 4 carbon atoms, and R3 is as defined above.
335892
Dansey Roger
Ellis Frank
Hartley David
Oxford Alexander W.
George H. Riches And Associates
Glaxo Group Limited
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