1,2,4-triazine derivatives for the inhibition of protein...

C - Chemistry – Metallurgy – 07 – D

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C07D 253/07 (2006.01) A61K 31/53 (2006.01) C07D 253/075 (2006.01) C07D 403/04 (2006.01) C07D 405/04 (2006.01) C07D 409/04 (2006.01)

Patent

CA 2249999

The present invention relates to compositions and methods for inhibiting nonenzymatic cross-linking (protein aging). Accordingly, a composition is disclosed which comprises a substituted 1,2,4-triazine of formula (I) and the biologically and pharmaceutically acceptable salts thereof; capable of inhibiting the formation of advanced glycosylation endproducts of target proteins. The method comprises contacting the target protein with the composition. Both industrial and therapeutic applications for the invention are envisioned, as food spoilage and animal protein aging can be treated.

Compositions et procédés destinés à l'inhibition de la réticulation non enzymatique (vieillissement des protéines). La composition décrite comprend une 1,2,4-triazine substituée de la formule (I) et ses sels biologiquement et pharmaceutiquement acceptables, qui peuvent inhiber la formation des produits définitifs de la glycosylation avancée de protéines cibles. Ce procédé consiste à mettre la protéine cible en contact avec la composition. Des applications tant industrielles que thérapeutiques sont envisagées pour cette invention, dans la mesure où elle permet de traiter aussi bien la dégradation des aliments que le vieillissement des protéines animales.

LandOfFree

Say what you really think

Search LandOfFree.com for Canadian inventors and patents. Rate them and share your experience with other people.

Rating

1,2,4-triazine derivatives for the inhibition of protein... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 1,2,4-triazine derivatives for the inhibition of protein..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 1,2,4-triazine derivatives for the inhibition of protein... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFCA-PAI-O-1903480

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.