1,2,4-triazinylthiomethyl-3-cepheme sulfoxide procedure for...

Details 1,2,4-triazinylthiomethyl-3-cepheme sulfoxide procedure for... 1,2,4-triazinylthiomethyl-3-cepheme sulfoxide procedure for...

C - Chemistry, Metallurgy

07

D

260/104.1

C07D 501/56 (2006.01) C07D 501/00 (2006.01)

Patent

CA 1173434

ABSTRACT OF THE DISCLOSURE The present invention concern 3-(hydroxy-1,2,4-triasinyl) thiomethyl cephalosporines with formulae : Image IV in which : . R represents a line Image or a line Image . R' is hydrogen or a COOX' carboxyl group . R" and R''' can be identical or different, each representing a hydrogen or a lower alkil group or together a 1,3- propyline or 1,4- butyline radical. . X and X', which can be identical or different, represent hydrogen or a cation or an easily hydrolizable or metabolically labile and pharmaceutically acceptable ester or hemiacetal. - procedure for preparation of these cephalosporines and pharmaceutical dose forms containing them as active principles.

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