[1, 2, 4] triazolo [1, 5 -a] pyridines as kinase inhibitors

Details [1, 2, 4] triazolo [1, 5 -a] pyridines as kinase inhibitors [1, 2, 4] triazolo [1, 5 -a] pyridines as kinase inhibitors

C - Chemistry, Metallurgy

07

D

C07D 471/04 (2006.01) A61K 31/437 (2006.01) A61P 27/02 (2006.01)

Patent

CA 2751517

The invention is directed to certain novel compounds, methods for producing them and methods for treating or ameliorating a kinase-mediated disorder. More particularly, this invention is directed to substituted triazolopyridine compounds useful as selective kinase inhibitors, methods for producing such compounds and methods for treating or ameliorating a kinase-mediated disorder. In particular, the methods relate to treating or ameliorating a kinase-mediated disorder including cardiovascular diseases, diabetes, diabetes-associated disorders, inflammatory diseases, immunological disorders, cancer and diseases of the eye such as retinopathies or macular degeneration or other vitreoretinal diseases, and the like.

La présente invention concerne certains nouveaux composés, des procédés de production de ceux-ci, et des méthodes de traitement ou d'amélioration d'une maladie médiée par des kinases. Plus particulièrement, la présente invention concerne des composés de triazolopyridine de substitution utiles en tant qu'inhibiteurs sélectifs de kinases, des procédés de production de ces composés, et des méthodes de traitement ou d'amélioration d'un trouble médié par les kinases. En particulier, lesdites méthodes portent sur le traitement ou l'amélioration d'un trouble médié par des kinases, notamment une maladie cardiovasculaire, le diabète, un trouble lié au diabète, une maladie inflammatoire, un trouble immunologique, le cancer, une maladie oculaire, telle que la rétinopathie ou la dégénérescence maculaire ou une autre maladie vitréorétinienne, et analogues.

Affiliated with

Also associated with

Rating

[1, 2, 4] triazolo [1, 5 -a] pyridines as kinase inhibitors does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with [1, 2, 4] triazolo [1, 5 -a] pyridines as kinase inhibitors, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and [1, 2, 4] triazolo [1, 5 -a] pyridines as kinase inhibitors will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1636657