[1,2,4,]triazolo[4,3-a]quinaxoline derivatives, their...

Details [1,2,4,]triazolo[4,3-a]quinaxoline derivatives, their... [1,2,4,]triazolo[4,3-a]quinaxoline derivatives, their...

C - Chemistry, Metallurgy

07

F

C07F 9/6561 (2006.01) A61K 31/495 (2006.01) A61K 31/675 (2006.01) C07D 471/14 (2006.01) C07D 487/04 (2006.01) C07D 491/147 (2006.01)

Patent

CA 2158545

Quinoxaline compounds of general formula (I) wherein R1 is COX', POX'X" or alkyl substituted with COX" OR POX'X", and X' and X" independently are hydroxy or alkoxy, and R6, R7, R8 and R9 independently are hydrogen, alkyl, halogen, NH2, NO2, CN, CF3, SO2NY'Y" or COZ' wherein Z' is NY'Y" or alkyl and Y' and Y" independently are hydrogen or alkyl, triazolyl, imidazolyl, imidazolyl substituted with phenyl or alkyl, or R6 and R7, or R8 and R9, together form a further fused ring, are useful in the treatment of indications caused by hyperactivity of the excitatory neurotransmitters.

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