1,2,4-trioxanes related to arteanniun

C - Chemistry – Metallurgy – 07 – H

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167/202, 204/91.

C07H 9/04 (2006.01) A61K 31/70 (2006.01) C07D 493/10 (2006.01)

Patent

CA 1333393

Aretanniun derivatives can be made by photo-oxygenation of a 2-oxabicyclo[4.4.0]dec-1,8a-ene compound using singlet oxygen, and reaction with a carbonyl compound R1 R2 C=O to give a seco-desoxyarteannuin derivative subsituted with R1 and R2 at the 2-position.

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