C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/239.1
C07D 487/04 (2006.01) C07D 498/04 (2006.01) C07D 513/04 (2006.01)
Patent
CA 1126729
ABSTRACT OF THE DISCLOSURE Compounds of [1,2]anellated-7-phenyl-1,4-benzo- diazepines having the Formula I Image wherein X is oxygen, sulfur or NR; R is H, C1-C5 alkyl, C1-C5 alkyl, substituted with a terminal phenyl group, which is unsubstituted or substituted by one or 2 methoxy groups, a 3,4-methylenedioxy or 3,4-ethylenedioxy group, C2-C5 alkyl, substituted with terminal halogen, hydroxy or methoxy or, C3-C5 alkenyl R1, R2, R3, R4 and R5 are the same or different and are H, halogen, trifluoromethyl, nitro, alkyl, alkoxy, or alkylthio wherein alkyl is C1-C4 alkyl or two neighboring groups represent a methylenedioxy or ethylenedioxy group and the acid addition salts thereof, method for the preparation thereof, pharmaceutical compositions containing these com- pounds and methods of medical treatment using same.
333936
Hell Insa
Hueschens Rolf
Liepmann Hans
Milkowski Wolfgang
Wolf Klaus-Ullrich
Solvay Pharmaceuticals Gmbh
Swabey Ogilvy Renault
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