1-(2-aryl-1,3-dioxan-2-ylmethyl)-1h-imidazoles and...

Details 1-(2-aryl-1,3-dioxan-2-ylmethyl)-1h-imidazoles and... 1-(2-aryl-1,3-dioxan-2-ylmethyl)-1h-imidazoles and...

C - Chemistry, Metallurgy

07

D

260/305, 167/9,

C07D 405/06 (2006.01) A01N 43/50 (2006.01) A01N 43/64 (2006.01) A01N 43/653 (2006.01) C07D 319/06 (2006.01) C07D 521/00 (2006.01)

Patent

CA 1164463

ABSTRACT Novel 1- (2-aryl-1,3-dioxan-2-ylmethyl)-1H-imidazoles and 1H-1,2,4-triazole derivatives of the formula Image (I) and the phytopharmaceutically acceptable acid addition salt-, metal salt complexes and stereochemically isomeric forms thereof, wherein R1,R2 and R3 are each independently selectet from the group consisting of hydrogen and halo, provided that at least one of R1, R2 and R3 is halo; Q is a member selected from the group consisting of CH and N; and X, Y and Z are each independently selected from the group consisting of hydrogen and C1-C8 alkyl, provided that at least one of X, Y and Z is other than hydrogen These compounds display antifungal and antibacterial activity.

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