1,2-dihydro-2-oxo-3-aminoquinoxalines; process for preparing...

Details 1,2-dihydro-2-oxo-3-aminoquinoxalines; process for preparing... 1,2-dihydro-2-oxo-3-aminoquinoxalines; process for preparing...

C - Chemistry, Metallurgy

07

D

C07D 241/44 (2006.01) A61K 31/495 (2006.01)

Patent

CA 2146462

1,2-dihydro-2-oxo-3-amino-quinoxaline derivatives of general formula (I) in which R1 and R2 are independently hydrogen or a straight of branched C1-C4 alkyl radical, R3 is a straight or branched C3-C6 alkyl, alkenyl or hydroxy-alkyl grouping, their salts with pharmaceutically acceptable acids, and a method for preparing them and their use in therapy are disclosed.

La présente invention concerne les dérivés de dihydro-1,2 oxo-2 amino-3 quinoxaline de formule générale (I) dans laquelle R1 et R2 représentent, indépendamment l'un et l'autre, l'hydrogène ou un radical alcoyle en C1-C4 linéaire ou ramifié, R3 re- présente un groupement alcoyle, alcényle ou hydroxy-alcoyle, en C3-C6 linéaire ou ramifié, leurs sels avec des acides phar- maceutiquement acceptables, ainsi que leur procédé de préparation et leur utilisation en thérapeutique.

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