1,2-diphenylethanolamine derivatives and their salts and the...

C - Chemistry – Metallurgy – 07 – D

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260/267.1, 260/2

C07D 401/04 (2006.01) C07D 213/76 (2006.01) C07D 295/04 (2006.01) C07D 295/084 (2006.01)

Patent

CA 1046515

Abstract of the Disclosure: 1,2-Diphenylathanolamine derivatives of the formula: Image wherein R1 and R2 are each hydrogen, a halogen, nitro, hydroxy, an alkyl or methoxy: R3 is a group of the formula: Image wherein R4, R5 and R6 are each hydrogen, a halogen or methoxy and n is an integer of 0 to 3, or a pyridyl; and Z is hydroxy or an acyloxy; with proviso that when R1 and/or R2 are hydroxy, Z is hydroxy, and their pharmaceutically acceptable salts, which have excel- lent analgesic and anti-tussive activities, and a process for the preparation thereof. - 1 -

223033

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